CONTINUOUS FLOW-INJECTION ATOMIC-ABSORPTION SPECTROMETRIC METHOD FOR THE DETERMINATION OF ONDANSETRON

Authors
ZAMORA LL CALATAYUD JM
Citation
Ll. Zamora et Jm. Calatayud, CONTINUOUS FLOW-INJECTION ATOMIC-ABSORPTION SPECTROMETRIC METHOD FOR THE DETERMINATION OF ONDANSETRON, Analytica chimica acta, 300(1-3), 1995, pp. 143-148
Citations number
12
Categorie Soggetti
Chemistry Analytical
Journal title
Analytica chimica acta → ACNP
ISSN journal
00032670
Volume
300
Issue
1-3
Year of publication
1995
Pages
143 - 148
Database
ISI
SICI code
0003-2670(1995)300:1-3<143:CFASMF>2.0.ZU;2-E
Abstract
A flow-injection procedure for the indirect determination of the new d rug Ondansetron is proposed. The method is based on the reaction of th e drug in an oxidative solid-phase reactor included in the flow assemb ly. The reactor was made by lead dioxide physically entrapped by polym erization; the released lead(II) was monitored by atomic absorption sp ectrometry at 217.0 nm. The procedure gave a linear calibration graph up to 20 mu g ml(-1) of Ondansetron with a sample throughput of 338 sa mples h(-1).