RESISTANCE OF 310 GRAM-POSITIVE STRAINS I SOLATED FROM MILKING COW UDDERS TO ANTISEPTICS AND ANTIBIOTICS AFTER USE OF POST-MILKING TEAT GERMICIDES

The sensitivity of 310 Gram-positive strains, isolated from milking co ws udders, to 4 antiseptics (cetrimide, chlorhexidine, hexachlorophene and mercury) and 9 antibiotics (ampicillin, streptomycin, erythromyci n, chloramphenicol, kanamycin, tetracycline, gentamycin, novobiocin an d oxacillin) was determined. The statistical analysis of correlation w as carried out for the bacterial species studied (Staphylococcus, Stre ptococcus and Bacillus), the scattering of the minimum inhibitory conc entrations of which has proved to be statistically heterogeneous towar ds antiseptics and antibiotics. This analysis revealed positive links between chlorhexidine and 5 antibiotics for Streptococcus and between hexachlorophene and oxacillin for Bacillus. The analysis of results at the level of bacterial species, taking into account a loss of sensiti vity of 4 times the modal minimum inhibitory concentration of the spec ies reveals the importance of the strains which are resistant to many antibiotics and especially the Enterococcus and the species Staphyloco ccus epidermidis. indeed, these strains are possible reservoirs of pla smids of resistance to antibiotics and antiseptics.