PERIODONTAL INDEXES OF PATIENTS TAKING ISONIAZID AND RIFAMPIN - A PILOT-STUDY

A significant reduction in the incidence of tuberculosis (TB) has resu lted from the use of medications such as isoniazid (MH) and rifampin. Unfortunately, there has been a resurgence of TB since the mid 1980s, The purpose of this pilot study was to evaluate the effects of INH and rifampin on periodontal indices of patients with positive tuberculin skin tests (PPD), The gingival index, plaque index, and periodontal sc oring and recording were recorded in PPD-positive patients at baseline and 1 month, Control patients received no medications during the stud y and were evaluated at baseline and 1 month, Mean values for each pat ient were obtained and analyzed using unpaired t tests (N = 8), Statis tically, within the limits of this study, it was found that patients t aking INH and/or rifampin had a significant decrease (p < 0.05) in gin gival inflammation from baseline.