Asymptomatic nonsustained ventricular tachycardia and complex ventricu
lar arrhythmias in elderly persons without heart disease should not be
treated with antiarrhythmic drugs. Nonsustained ventricular tachycard
ia and complex ventricular arrhythmias in elderly persons are associat
ed with an increased incidence of coronary events, primary ventricular
fibrillation and sudden cardiac death, especially if abnormal left ve
ntricular ejection fraction, left ventricular hypertrophy or silent is
chaemia are present. beta-Blockers should be used in the treatment of
elderly patients with ventricular tachycardia or complex ventricular a
rrhythmias associated with ischaemic or nonischaemic heart disease if
there are no contraindications to beta-blocker therapy. I would reserv
e the use of amiodarone in the treatment of ventricular tachycardia or
complex ventricular arrhythmias to life-threatening ventricular tachy
arrhythmias in elderly patients who cannot tolerate or who do not resp
ond to beta-blockers.