GENERAL REMARKS ON THE THERMAL-DECOMPOSITION OF SOME DRUGS

Citation
M. Wesolowski et T. Konarski, GENERAL REMARKS ON THE THERMAL-DECOMPOSITION OF SOME DRUGS, Journal of thermal analysis, 43(1), 1995, pp. 279-289
Citations number
7
Categorie Soggetti
Chemistry Analytical
Journal title
ISSN journal
03684466
Volume
43
Issue
1
Year of publication
1995
Pages
279 - 289
Database
ISI
SICI code
0368-4466(1995)43:1<279:GROTTO>2.0.ZU;2-L
Abstract
The thermal decomposition of antituberculous, local anaesthetic and ca lcium salts of organic acids used as the drugs has been studied by dif ferential thermal and thermogravimetric techniques. General characteri stics of their thermal decomposition has been made. The effect of samp le size over the range 20-200 mg and heating rate over the range 3-15 deg.min(-1) on the thermal degradation has been investigated. The valu es of the kinetic parameters has been also determined.