F. Fulciniti et al., CALCIFYING EPITHELIAL ODONTOGENIC-TUMOR (PINDBORGS TUMOR) ON FINE-NEEDLE ASPIRATION BIOPSY SMEARS - A CASE-REPORT, Diagnostic cytopathology, 12(1), 1995, pp. 71-75
A 44-yr-old woman with a long-standing history of painful mandibular s
welling was hospitalized for the diagnostic evaluation of an osteolyti
c mandibular lesion in the premolar-canine area. Fine-needle aspiratio
n biopsy (FNAB) was performed and cytologic smears were characterized
by clusters, sheets, and rare isolated pleomorphic cells of the squamo
id type, blocks of amorphous material encircled by fibroblasts, and oc
casional calcifications. A cytological diagnosis of Pindborg's tumor w
as made, which was confirmed by histopathological examination. Evaluat
ion of DNA ploidy by semiautomated image cytometry produced an aneuplo
id histogram. The patient is free of residual neoplasm at a 12-mo post
-operative interval. The cytological differential diagnosis of this ra
re odontogenic neoplasm is discussed briefly. (C) 1995 Wiley-Liss, Inc
.