J. Karrholm et al., INCREASED METAL RELEASE FROM CEMENTED FEMORAL COMPONENTS MADE OF TITANIUM-ALLOY - 19 HIP PROSTHESES FOLLOWED WITH RADIOSTEREOMETRY (RSA), Acta orthopaedica Scandinavica, 65(6), 1994, pp. 599-604
In 19 patients the concentrations of metal were measured in serum, uri
ne and joint fluid 2 years after implantation of uncemented commercial
ly pure titanium acetabular cups and cemented or uncemented femoral co
mponents made of titanium alloy. A ceramic against the polyethylene ar
ticulation was used. The fixation of the components was followed with
radiostereometry (RSA). Samples from 12 patients scheduled for hip or
knee prostheses and without any metallic implant were used as controls
. High levels of titanium were found in cemented hips and when large a
cetabular cups had been inserted. Increased aluminum levels were also
noted in the cemented hips. Vanadium was not detected in any of the sa
mples. Micromotions were detected in most of the implants, but the mag
nitude of these movements could not be used to predict the release of
metal into the synovial fluid.