EFFICIENT SYNTHESIS OF AMINONAPHTHOQUINONES AND AZIDOBENZOHYDROQUINONES - MECHANISTIC CONSIDERATIONS OF THE REACTION OF HYDRAZOIC ACID WITHQUINONES, AN OVERVIEW
Ea. Couladouros et al., EFFICIENT SYNTHESIS OF AMINONAPHTHOQUINONES AND AZIDOBENZOHYDROQUINONES - MECHANISTIC CONSIDERATIONS OF THE REACTION OF HYDRAZOIC ACID WITHQUINONES, AN OVERVIEW, Journal of organic chemistry, 62(1), 1997, pp. 6-10
Parameters useful to predict and control the reaction outcome of conju
gate addition of hydrazoic acid to quinones have been studied, and the
optimum conditions for the efficient synthesis of aminonaphthoquinone
s and azidobenzohydroquinones are reported. The application of this re
action for the efficient formal synthesis of dephostatin is also prese
nted.