COLITIS ULCEROSA COMPLICATED BY MALIGNANT-LYMPHOMA - CASE-REPORT AND ANALYSIS OF PUBLISHED WORKS

A 51 year old woman with a two year history of ulcerative colitis deve loped a wide spread gastrointestinal non-Hodgkin's lymphoma of low gra de malignancy (MALT-lymphoma) involving upper and lower gastrointestin al tract, spleen, and bone marrow. After chemotherapy, clinical sympto ms improved and lymphocytic infiltrates disappeared. Thirty nine cases of ulcerative colitis and 22 cases of Crohn's disease complicated by gastrointestinal lymphomas reported in published works are reviewed. I n inflammatory bowel diseases any dense lymphocytic infiltrates seen i n biopsy specimens obtained from ulcerative colitis or Crohn's disease should be assessed to exclude gastrointestinal lymphoma.