An automatic data processing and display protocol for proton magnetic
resonance spectroscopic imaging is described. The spectroscopic images
are generated using the fitted peak areas of phased metabolite resona
nces using the Levenberg-Marquardt algorithm. This automated spectrosc
opic image processing is tested and evaluated using phantom and human
brain data. This algorithm is robust, simple to use, and minimizes use
r bias in processing and quantifying serial changes of metabolite leve
ls in brain tissue. (C) 1995 Academic Press,Inc.