ROLE OF ANDROGENS IN THE DEVELOPMENTAL BIOLOGY OF THE PILOSEBACEOUS UNIT

Authors
ROSENFIELD RL DEPLEWSKI D
Citation
Rl. Rosenfield et D. Deplewski, ROLE OF ANDROGENS IN THE DEVELOPMENTAL BIOLOGY OF THE PILOSEBACEOUS UNIT, The American journal of medicine, 98, 1995, pp. 80-88
Citations number
69
Categorie Soggetti
Medicine, General & Internal
Journal title
The American journal of medicine → ACNP
ISSN journal
00029343
Volume
98
Year of publication
1995
Supplement
1A
Pages
80 - 88
Database
ISI
SICI code
0002-9343(1995)98:<80:ROAITD>2.0.ZU;2-3
Abstract
The growth and development of pilosebaceous units in their characteris tic pattern depends on the interaction of androgens and diverse biolog ic factors. Stromal-epithelial interactions are essential features. Co nsiderable evidence suggests that androgens stimulate the growth of se nsitive pilosebaceous units primarily by acting on specific stromal ce lls and that androgens and retinoic acid interact to regulate specific stages of sebocyte differentiation.