Twelve patients with suspected or proven spinal cord disease were stud
ied with a fluid attenuated repeated echo sequence employing a fast sp
in-echo data acquisition (Turbo-FLAIR) and the results were compared w
ith those obtained with conventional T-1- and T-2- weighted spin-echo
sequences. The Turbo-FLAIR sequence utilized an unselected 180 degrees
pulse to reduce the signal from CSF followed by a spin-echo sequence
based on the Rapid Acquisition with Relaxation Enhancement (RARE) puls
e sequence for data acquisition. Three and four echo versions were use
d. Four low signal intensity lesions (cysts or syrinxes) were seen of
which three were better seen with the Turbo-FLAIR sequence than with t
he other sequences, The remaining lesion was equally web seen. Of the
seven high signal lesions found, six were better seen with the Turbo-F
LAIR sequence and one was equally well seen. The Turbo-FLAIR sequence
is more rapid than the T-2-weighted spin-echo sequence and compares fa
vourably with the combined results of both the T-1- and T-2-weighted s
pin-echo sequences for lesion conspicuity.