Cj. Easton et al., ARYL NITRILE OXIDE CYCLOADDITION REACTIONS IN THE PRESENCE OF BAKERS-YEAST AND BETA-CYCLODEXTRIN, Tetrahedron letters, 36(4), 1995, pp. 629-632
Contrary to recent reports, baker's yeast is not required for reaction
s of nitrile oxides with either ethyl cinnamate or 4-vinylpyridine to
give isoxazolines. beta-Cyclodextrin may alter the ratio of isomers is
olated from the reactions of the cinnamate but only at concentrations
of reactants much lower than those reported, and this effect is most l
ikely due to selective product complexation rather than selective prod
uct formation.