TAILORED CORRELATION SPECTROSCOPY FOR THE ENHANCEMENT OF FINGERPRINT CROSS PEAKS IN PEPTIDES AND PROTEINS

Authors
QUANT J PRASCH T IHRINGER S GLASER SJ
Citation
J. Quant et al., TAILORED CORRELATION SPECTROSCOPY FOR THE ENHANCEMENT OF FINGERPRINT CROSS PEAKS IN PEPTIDES AND PROTEINS, Journal of magnetic resonance. Series B, 106(2), 1995, pp. 116-121
Citations number
21
Categorie Soggetti
Physics, Atomic, Molecular & Chemical
Journal title
Journal of magnetic resonance. Series B → ACNP
ISSN journal
10641866
Volume
106
Issue
2
Year of publication
1995
Pages
116 - 121
Database
ISI
SICI code
1064-1866(1995)106:2<116:TCSFTE>2.0.ZU;2-H
Abstract
A new experimental mixing scheme for band-selective Hartmann-Hahn tran sfer between the H-N and H-alpha resonances of peptides and proteins i s presented. This form of tailored correlation spectroscopy (TACSY) al lows enhancement of the sensitivity of specific (H-N-H-alpha)-fingerpr int signals compared to broadband TOCSY experiments. The design criter ia as well as experimental applications of the multiple-pulse sequence CABBY-1 are presented. (C) 1995 Academic Press, Inc.