PREPARATION OF SECONDARY ALKYL AND BENZYLIC ZINC BROMIDES USING ACTIVATED ZINC METAL DEPOSITED ON TITANIUM-OXIDE

Authors
STADTMULLER H GREVE B LENNICK K CHAIR A KNOCHEL P
Citation
H. Stadtmuller et al., PREPARATION OF SECONDARY ALKYL AND BENZYLIC ZINC BROMIDES USING ACTIVATED ZINC METAL DEPOSITED ON TITANIUM-OXIDE, Synthesis, (1), 1995, pp. 69-72
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
1
Year of publication
1995
Pages
69 - 72
Database
ISI
SICI code
0039-7881(1995):1<69:POSAAB>2.0.ZU;2-R
Abstract
Sodium dispersed on titanium oxide readily reduces zinc chloride leadi ng to a highly active zinc powder which inserts into secondary alkyl a nd benzylic bromides under mild conditions, producing the correspondin g zinc reagents in high yields. Compared to zinc dust, this activated zinc allows the preparation of secondary benzylic zinc bromides with s ignificantly less Wurtz-coupling products.