CYTOTOXIC CONSTITUENTS OF BURSERA-PERMOLLIS

Authors
WICKRAMARATNE DBM MAR W CHAI H CASTILLO JJ FARNSWORTH NR SOEJARTO DD CORDELL GA PEZZUTO JM KINGHORN AD
Citation
Dbm. Wickramaratne et al., CYTOTOXIC CONSTITUENTS OF BURSERA-PERMOLLIS, Planta medica, 61(1), 1995, pp. 80-81
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
61
Issue
1
Year of publication
1995
Pages
80 - 81
Database
ISI
SICI code
0032-0943(1995)61:1<80:CCOB>2.0.ZU;2-C
Abstract
Four cytotoxic lignans were isolated from the stem bark of Bursera per mollis (Burseraceae), namely, deoxypodophyllotoxin (1), beta-peltatin methyl ether (2), picro-beta-peltatin methyl ether (3), and dehydro-be ta-peltatin methyl ether (4). Also isolated was the inactive lignan, n emerosin (5). Compounds 1 and 2 were potently cytotoxic when evaluated against a panel of human cancer cell lines.