NEW SYNTHETIC ROUTE TO 1,2,4-THIADIAZOLINES AND 1,3-THIAZOLINES VIA THIADIAZOLOPYRIDINIUM SALTS

Authors
MARTINEZ A CASTRO A FONSECA I MARTINEZRIPOLL M CANO FH ALBERT A
Citation
A. Martinez et al., NEW SYNTHETIC ROUTE TO 1,2,4-THIADIAZOLINES AND 1,3-THIAZOLINES VIA THIADIAZOLOPYRIDINIUM SALTS, Heterocycles, 43(12), 1996, pp. 2657-2666
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
12
Year of publication
1996
Pages
2657 - 2666
Database
ISI
SICI code
0385-5414(1996)43:12<2657:NSRT1A>2.0.ZU;2-C
Abstract
A new efficient synthesis of 1,2,4-thiadiazolidines and 1,3-thiazolidi nes bearing 2-pyridylimino substituents using thiadiazolopyridinium ch lorides as intermediates is described. The mechanism probably involves a base promoted nucleophilic addition of thiadiazolopyridinium salts to nitriles and ketones.