A. Puca et al., EVALUATION OF 5TH NERVE DYSFUNCTION IN 136 PATIENTS WITH MIDDLE AND POSTERIOR CRANIAL FOSSAE TUMORS, European neurology, 35(1), 1995, pp. 33-37
One-hundred thirty-six patients operated on for extra-axial tumors of
the posterior and middle cranial fossae were retrospectively evaluated
to define the relevance of trigeminal nerve dysfunction and to correl
ate clinical and surgical observations. The following data are reporte
d: tumor types, presence of specific trigeminal symptoms and signs, me
an duration of symptomatology, anatomical relation between tumor and f
ifth nerve. Trigeminal symptoms were present in 45 subjects (33.08%) w
ith a mean duration of 23.56 months. Frequency of symptoms was differe
nt in various oncotypes. Fifth nerve disturbances were the symptom of
onset in 18 subjects (13.23%). A tumoral involvement of the nerve was
reported at surgery in 73 patients (53.67%) and was defined as contact
, compression or infiltration. Postoperatively, 12 patients showed an
improvement of fifth nerve disturbances. A statistically significant d
ifference (p < 0.05) was found in: (1) the incidence of symptoms in pa
tients with and in those without anatomical trigeminal involvement: (2
) the incidence of signs in the same groups; (3) the incidence of post
operative relief in patients with fifth nerve compression compared to
patients with different surgical findings; (4) the incidence of postop
erative relief in patients with typical trigeminal neuralgia compared
to those with other symptoms.