STRUCTURE ELUCIDATION AND SYNTHESIS OF A METABOLITE OF ANTIINFLAMMATORY DRUG DUP-697

Authors
NAKAMURA S KONDO M GOTO K NAKAMURA M TSUDA Y SHISHIDO K
Citation
S. Nakamura et al., STRUCTURE ELUCIDATION AND SYNTHESIS OF A METABOLITE OF ANTIINFLAMMATORY DRUG DUP-697, Heterocycles, 43(12), 1996, pp. 2747-2755
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
12
Year of publication
1996
Pages
2747 - 2755
Database
ISI
SICI code
0385-5414(1996)43:12<2747:SEASOA>2.0.ZU;2-B
Abstract
Structure of the O-glucuronide (2), one of the metabolites of antiinfl ammatory drug DUP 697 (1), has been elucidated on the basis of spectra l data and a total synthesis of it has been accomplished. Since the sy nthetic route to 2 is an unambiguous one, completion of the synthesis established the assigned structure.