Objective: To discuss two cases of the T4 syndrome in order to raise a
wareness and aid its clinical recognition. Clinical Features: Paresthe
sias, numbness, or upper extremity pains associated with or without he
adaches and upper back stiffness characterize the T4 syndrome. In addi
tion, no hard neurological signs are present. Upper thoracic joint dys
function, especially in the region of the T4 segment, appeared to be t
he major cause of the upper extremity symptoms and headaches. A nontra
umatic onset is common and the peculiar glove-like distribution of han
d or forearm pain can often lead to a mistaken diagnosis, including ps
ychogenesis. Intervention and Outcome: Joint manipulation, stretching,
and strengthening exercises directed at the upper thoracic dysfunctio
nal segments were used with good results. Conclusion: Upper extremity
symptoms of nocturnal or early morning paresthesias, especially in a g
love-like distribution, coupled with headaches and a stiff upper thora
cic spine without neurological signs of disease may indicate a T4 synd
rome. Manipulation of the dysfunctional upper thoracic segments may re
lieve these symptoms.