M. Brophey et al., PROMINENT SMALL-BOWEL GA-67 UPTAKE ASSOCIATED WITH YERSINIAL AND TUBERCULOUS ENTEROCOLITIS, Clinical nuclear medicine, 20(2), 1995, pp. 107-110
The nuclear medicine evaluation of the immunocompromised patient with
fever of unknown origin may include the use of either labeled leukocyt
es or Ga-67 citrate, or both, in the search for an infectious focus. I
n recent years, labeled leukocytes (In-111 or Tc-99m) seem to have bee
n employed preferentially by some. This is especially the case when th
e abdomen is a suspected site of involvement because of the normal col
onic excretion of gallium that may complicate the interpretation of th
is study. The authors present the case of an immunocompromised patient
with the interesting scintigraphic pattern of diffuse large and small
bowel uptake of gallium secondary to biopsy proven Yersinia and tuber
culous enterocolitis. A review of the recent literature reveals only o
ne other similar case in which Yersinial disease was detected by Ga-67
scintigraphy. The present case illustrates that gallium's avidity for
the atypical, less pyogenic, opportunistic infections common in immun
ocompromised patients justifies its continued use in such settings and
, specifically, whenever tuberculosis is suspected.