A 43-yr-old man was referred for any possible parathyroid abnormality
that could explain his hypercalcemia and slightly increased parathormo
ne levels. The thallium-technetium scan showed a diffuse abnormal thal
lium uptake incidentally in the bone marrow, otherwise parathyroid sca
n appearance was normal. He had an essentially normal bone scan, altho
ugh subsequent nanocolloid scintigraphy demonstrated bone marrow expan
sion. Further investigations, including a bone marrow aspiration biops
y, confirmed the diagnosis of nonsecretory myeloma. This finding sugge
sts that Tl-201 imaging can be a useful tool to investigate those pati
ents suffering from similar myeloid disorders causing bone marrow hype
rplasia.