IN-VIVO COMPARISON OF DIFFERENT QUANTITATIVE EDGE-DETECTION SYSTEMS USED FOR MEASURING CORONARY ARTERIAL DIAMETERS

Three different systems for quantitative coronary analysis [Cardiovasc ular Measurement System (CMS(R)); Polytron 1000(R); Angiographic Works tation (AWOS(R))] were compared in 109 patients before and after coron ary angioplasty and at follow-up coronary angiography, Correlation coe fficients were low and 95% limits of agreement were wide, In general, CMS(R) exhibited a tendency to yield lower values for very small diame ters and higher values for larger vessels, The acute gain in minimal l uminal diameter was considerably smaller when assessed by AWOS(R) as c ompared to Polytron(R) (0.52 vs. 0.71 mm, P < .0001) and to CMS(R) (0. 52 vs. 0.75 mm, P < .0001). Long-term gain was much larger when assess ed by Polytron(R) as compared to AWOS(R) (18.8 vs. 11.5%, P < .001) an d it was almost double for CMS(R) as compared to AWOS(R) (20.7 vs. 11. 5%, P < .0001), In conclusion, in the individual patient very differen t results can be obtained when different QCA systems are used, and sys tematic differences between the systems are encountered, (C) 1995 Wile y-Liss, Inc.