A major goal of many poultry producers is to attain good flock liveabi
lity Historically, most poultry producers have manipulated environment
al conditions and management to maximize bird health. In the past two
decades there has been much research into nutritional regimes that imp
rove bird health through immunomodulation. Commercial poultry environm
ents contain ubiquitous micro-organisms that continuously challenge th
e immune system. Nutritional supplements that enhance immune system fu
nction may improve flock performance and be economically advantageous.
This paper reviews the literature on zinc-methionine and the avian ce
llular immune system. Current knowledge of the effects of zinc on many
animal models is reviewed and a hypothetical mechanism for the action
of zinc-methionine on this system is discussed.