Epidemiological screening carried out in Libya revealed 1539 patients
with zoonotic skin leishmaniasis who were treated, with consideration
for the indications, by glucantine, lincocine, vibramycin, keflex, amo
xil, tigason, nisoral, and levamisole. Good results were attained in 1
237 (80.3%) patients. In 302 (19.7%) patients the treatment was ineffe
ctive; laboratory tests revealed in their blood a marked deficit of py
ridoxine. An extra course of therapy of these patients with vitamin B6
preparations pyriditol and pyridoxal phosphate was conductive to comp
lete cure of these patients and recovery of normal pyridoxine level in
the blood.