An. Rodionov et al., NATURAL-KILLER ACTIVITY IN ASSESSMENT OF THE TIME-COURSE OF TUMOR PROGRESS AND IMMUNOBIOLOGICAL SURVEILLANCE IN LOW-MALIGNANT SKIN LYMPHOMAS, Vestnik dermatologii i venerologii, (5), 1994, pp. 4-5
Natural killer functional activity is normal at early stages of tumor
process in patients with low-malignant skin lymphomas; this parameter
is suppressed after 15-20 years of the disease. Leakadin in a total do
se 10 g and prednisolone in maintenance doses suppressed natural kille
r activity, whereas prospidin in a total dose 4 g did not show such an
effect. Thymalin or thymogen normalized natural killer activity.