LEUKEMIA, LYMPHOGRANULOMATOSIS AND HISTIO CYTOSIS OF LANGERHANS IN CHILDREN WITH A HISTORY OF ENLARGED THYMUS

The group consisted of 1056 children with enlarged thymus and a monito red catamnesis in 317 of 0.5-23 years. In 5 examinations in different periods after the diagnosis of enlarged thymus, haematological maligna ncies were diagnosed: acute lymphoblastic leukaemina (2 children), lym phogranulomatosis (1 child), chronic myeloid leukaemia (monocytic vari ant) and histiocytosis of Langerhans (1 child). The comparison of thes e data with other publications on the prevalence of these diseases in the population and the rate of mortality in Moscow place the children with enlarged thymus to high-risk group for haematological malignancie s.