The present study reports the clinical features of two AIDS patients i
nfected by Cyclospora. According to our observations, Cyclospora in AI
DS can be responsible both for gastroenteritis and for asymptomatic in
fections with spontaneous rapid clearance. In addition, and undiagnose
d circulation of this agent in Italy could be hypothesized: neither pa
tient had a past history of foreign travel. These are the first two ca
ses in AIDS described in Italy.