STRUCTURE AND FUNCTION OF TITIN AND NEBULIN

Authors
Citation
Cs. Keller, STRUCTURE AND FUNCTION OF TITIN AND NEBULIN, Current opinion in cell biology, 7(1), 1995, pp. 32-38
Citations number
76
Categorie Soggetti
Cell Biology
ISSN journal
09550674
Volume
7
Issue
1
Year of publication
1995
Pages
32 - 38
Database
ISI
SICI code
0955-0674(1995)7:1<32:SAFOTA>2.0.ZU;2-P
Abstract
Recent investigations of titin anchorage and elasticity have been supp lemented with in vitro expression studies on isolated domains of titin and nebulin. These have yielded new insights into the molecular basis of the functions of these proteins in muscle. The characterization of a cellular (non-muscle) isoform of titin has extended the functional relevance of this family of proteins beyond the realm of muscle.