SOUTHWEST-ONCOLOGY-GROUP STRATEGIES IN PROSTATIC-CARCINOMA

The Southwest Oncology Group Genitourinary Committee evolved in 1978 f rom a combined gynecologic-urologic cancer committee. A significant ca talyst in this development was the growing interest in prostatic carci noma, with an initial focus on hormone refractory disease. Clinical st udies have expanded into combined androgen blockade, untreated metasta tic disease and localized prostate cancer. Since 1978, more than forty trials in prostatic carcinoma have been conducted. Currently, seven a re in progress or under development. Conclusions and future directions are reviewed. (C) 1995 Wiley-Liss, Inc.