A COMPARISON OF THE ACCUMULATION OF NOVOBIOCIN INTO BACTERIA WITH ITSANTIBACTERIAL PROPERTIES

Authors
BARRETTBEE K PINDER P STAWPERT J
Citation
K. Barrettbee et al., A COMPARISON OF THE ACCUMULATION OF NOVOBIOCIN INTO BACTERIA WITH ITSANTIBACTERIAL PROPERTIES, Journal of antimicrobial chemotherapy, 34(6), 1994, pp. 1041-1045
Citations number
8
Categorie Soggetti
Microbiology,"Pharmacology & Pharmacy
Journal title
Journal of antimicrobial chemotherapy → ACNP
ISSN journal
03057453
Volume
34
Issue
6
Year of publication
1994
Pages
1041 - 1045
Database
ISI
SICI code
0305-7453(1994)34:6<1041:ACOTAO>2.0.ZU;2-O
Abstract
The accumulation of novobiocin in bacteria has been compared with the MIC, inhibition of DNA biosynthesis and inhibition of the activity of isolated DNA gyrase for a range of species. There was a good correlati on between MIC and the inhibition of DNA biosynthesis and DNA gyrase. Novobiocin accumulation did not correlate with any other parameter.