SOLUBLE COMBINATORIAL LIBRARIES OF ORGANIC, PEPTIDOMIMETIC AND PEPTIDE DIVERSITIES

Authors
BLONDELLE SE PEREZPAYA E DOOLEY CT PINILLA C HOUGHTEN RA
Citation
Se. Blondelle et al., SOLUBLE COMBINATORIAL LIBRARIES OF ORGANIC, PEPTIDOMIMETIC AND PEPTIDE DIVERSITIES, TrAC. Trends in analytical chemistry, 14(2), 1995, pp. 83-92
Citations number
47
Categorie Soggetti
Chemistry Analytical
Journal title
TrAC. Trends in analytical chemistry → ACNP
ISSN journal
01659936
Volume
14
Issue
2
Year of publication
1995
Pages
83 - 92
Database
ISI
SICI code
0165-9936(1995)14:2<83:SCLOOP>2.0.ZU;2-6
Abstract
Molecular diversity provides a source of novel lead compounds for drug discovery. In particular, soluble combinatorial libraries composed of millions of peptides, peptidomimetics and organic compounds have lead to the successful identification of new pharmacophores. The current d evelopment of structurally defined combinatorial libraries will broade n the applicability of combinatorial chemistry.