SIGNAL-TRANSDUCTION MECHANISMS IN MESENCHYMAL CELLS

Authors
MCALLISTER BS WALTERS JD OLSON MS
Citation
Bs. Mcallister et al., SIGNAL-TRANSDUCTION MECHANISMS IN MESENCHYMAL CELLS, Critical reviews in oral biology and medicine, 5(3-4), 1994, pp. 291-310
Citations number
NO
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Critical reviews in oral biology and medicine → ACNP
ISSN journal
10454411
Volume
5
Issue
3-4
Year of publication
1994
Pages
291 - 310
Database
ISI
SICI code
1045-4411(1994)5:3-4<291:SMIMC>2.0.ZU;2-W
Abstract
Mesenchymal cells are continually stimulated by a wide spectrum of bio logical mediators. These mediators bind to receptors on the cell surfa ce and initiate a cascade of signaling events. The initial signal tran sduction pathways known to be stimulated in mesenchymal cells include phospholipase C, phospholipase D, phospholipase A(2), adenylate cyclas e, receptor tyrosine kinases, and receptor serine/threonine kinases. T hese pathways are reviewed and specific applications for therapeutic i ntervention in wound healing and regenerative therapy in the periodont ium are discussed.