Sgj. Williams et al., HYPOKALEMIC RHABDOMYOLYSIS - AN UNUSUAL PRESENTATION OF CELIAC-DISEASE, European journal of gastroenterology & hepatology, 7(2), 1995, pp. 183-184
Objective: To describe the clinical presentation and management of a p
atient with hypokalaemic rhabdomyolysis secondary to coeliac disease.
Design: Retrospective study. Setting: Hospital based. Patient: A 60-ye
ar-old Caucasian man presenting with weakness caused by hypokalaemic r
habdomyolysis secondary to coeliac disease. Interventions: Following t
he diagnosis by jejunal biopsy, the patient was treated with both intr
avenous and oral potassium supplements, and a gluten-free diet. Outcom
e measures: Resolution of weakness and restitution of normal villous a
rchitecture following treatment. Results: The patient's myopathy respo
nded to the potassium supplements, his diarrhoea and histological chan
ges resolved while on the gluten-free diet. Conclusion: Patients with
coeliac disease may present with hypokalaemia in association with stea
torrhoea. If potassium loss is rapid, rhabdomyolysis may occur. Coelia
c disease should be considered a cause of malabsorption-induced hypoka
laemic rhabdomyolysis.