ABNORMAL CUTANEOUS VASOREACTIONS IN ATOPI CS DURING AND AFTER ACUTE ECZEMA

In atopic eczema patients the well-known abnormal cutaneous reactivity of the blood vessels (white dermographism, delayed blanch after acety lcholine, paradoxical blanching after nicotinic acid application and d iminished erythema after histamine injection) were observed during acu te eczematous episodes and later in an exzema-free state in comparison with controls. In this follow-up study the use of different stimuli a llowed us to demonstrate abnormal cutaneous vascular reactions in the patients depending on the severity of their atopic eczema. Severely af fected patients showed persistence of the paradoxical vascular reactio ns even in an eczema-free cutaneous state.