TEN PATIENTS (six men and four women; mean age, 40 yr) with spontaneou
s dissection of the basilar artery are reported. Clinically, six were
admitted with subarachnoid hemorrhage (SAH) and four were admitted wit
h brain stem ischemia. Angiography demonstrated string sign in four pa
tients, pearl reaction in four, double lumen in one, and arterial ecta
sia with mural retention of contrast medium in one. Magnetic resonance
imaging was performed in two patients. Follow-up angiograms or magnet
ic resonance angiography in six patients showed spontaneous healing in
two patients, improvement in two, progression in one, and no change i
n one. Nine patients were treated medically, and one underwent selecti
ve intravascular occlusion of the dissecting aneurysm. One patient die
d after further SAH, two remain severely disabled, three have residual
neurological deficit, and four are in good clinical condition. The mo
st interesting observations in this series include a relatively good c
ourse in a substantial number of patients and low further bleeding pot
ential after SAH, the late ''globular'' evolution, which may be favora
ble for reconstructive treatment, and the diagnostic value of associat
ed computed tomographic/angiographic findings. Surgical options in bas
ilar dissection are very poor; in some reported cases, wrapping has be
en tried with disappointing results. In light of the possibility of sp
ontaneous healing or improvement, wrapping should be reserved for only
those patients with recurrent SAH or angiographic progression of the
dissection.