Survival of patients with increasingly complex congenital heart diseas
e has produced a population of children and adolescents who are suscep
tible to subacute bacterial endocarditis (SEE). We report a child whos
e endocarditis went unrecognised, and who developed amyloidosis. Asymp
tomatic proteinuria, haematuria and renal impairment are occasionally
seen in SEE and usually indicate glomerulonephritis, Amyloidosis shoul
d also be suspected in children with long-standing bacterial endocardi
tis with proteinuria or other evidence of renal impairment, especially
if associated with organomegaly. The diagnosis is made by renal biops
y.