RENAL-TRANSPLANTATION AND CHRONIC DIALYSIS IN CHILDREN AND ADOLESCENTS - THE 1993 ANNUAL-REPORT OF THE NORTH-AMERICAN PEDIATRIC RENAL-TRANSPLANT COOPERATIVE STUDY

The 1993 North American Pediatric Renal Transplant Cooperative Study a nnual report summarizes data voluntarily contributed by 82 participati ng centers on 3,223 pediatric patients who received 2,819 renal transp lants from January 1987 through January 1993 and 999 independent cours es of dialysis from January 1992 through January 1993. In addition to updating information regarding trends and outcomes in pediatric renal transplantation presented in previous annual reports, 1st-year registr y data are presented regarding current practices and trends in chronic dialysis therapy for children and adolescents in North America. Livin g donor graft (LDG) survival rate was 90% at 1 year, 85% at 2 years an d 75% at 5 years post transplant. Cadaver graft (CG) survival rates we re 76%, 71% and 62% at 1, 2 and 5 years post transplant, respectively. Overall mortality post transplantation continues to be low (CG 6.8%, LDG 4%), mortality remains high in young infants. The dialysis cohort was generally younger than the transplantation cohort. In all age grou ps, peritoneal dialysis was utilized in the majority of pediatric pati ents and the overall incidence of peritonitis was 1 episode per 8.2 pa tient months. External percutaneous catheters were utilized as the pre dominant chronic hemodialysis access in the study, and access site inf ections ranged from 6.9% at 1 month to 13.5% at 6 months.