Sg. Patel et N. Kishore, THERMODYNAMICS OF NUCLEIC-ACID BASES AND NUCLEOSIDES IN WATER FROM 25-DEGREES-C TO 55-DEGREES-C, Journal of solution chemistry, 24(1), 1995, pp. 25-38
Specific heat capacities, apparent molar heat capacities, densities, a
nd ap parent molar volumes have been determined for cytosine, uracil,
thymine, adenine, cytidine, 2'-deoxycytidine, uridine, thymidine and a
denosine at temperatures from 25 degrees C to 55 degrees C. The result
s of these measurements have been used to calculate for the first time
, the thermodynamic quantities: C-p,2(o), (partial derivative C-p,2(o)
/partial derivative T)(p), (partial derivative(2)C(p,2)(o)/partial der
ivative T-2)(p), V-2(o), (partial derivative V-2(o)/partial derivative
T)(p), and (partial derivative(2)V(2)(o)/partial derivative T-2)(p).
The -CH2- group contribution has been calculated at different temperat
ures. It has also been observed from the data for the nucleic acid bas
es and nucleosides that the additivity rule C-p,2(o)(nucleoside) - C-p
,2(o)(base) + C-p,2(o)(water) = C-p,2(o)(ribose) does not hold in thes
e cases.