A. Altes et al., HEPARIN-INDUCED THROMBOCYTOPENIA AND HEART OPERATION - MANAGEMENT WITH TEDELPARIN, The Annals of thoracic surgery, 59(2), 1995, pp. 508-509
Anticoagulation for cardiopulmonary bypass in the infrequent clinical
setting of thrombocytopenia associated with the use of unfractionated
heparin is a very serious problem. We describe a case in which a low-m
olecular-weight heparin (tedelparin) was selected for this purpose bas
ed on a platelet aggregation test, permitting adequate anticoagulation
during cardiopulmonary bypass for valve replacement. This case report
might help establish an adequate anticoagulation protocol when faced
with a patient suffering from this condition.