P. Droescher et J. Romer, SYNTHESIS OF HIGH SPECIFIC ACTIVITY YDROXY-[14-ALPHA,15-ALPHA-H-3]ESTRA-4,9-DIEN-3-ONE, Journal of labelled compounds & radiopharmaceuticals, 36(2), 1995, pp. 111-119
An improved synthesis of the tritium labelled form of the new pharmaco
n DIENOGEST is described. The [14 alpha,15 alpha-H-3]DIENOGEST was obt
ained with a specific activity of 51 Ci/mmol and a radiochemical purit
y > 98%.