EFFECT OF N-ACYLETHANOLAMINES ON TROUT ERYTHROCYTES

The biochemical effect of N-acylethanolamines on trout erythrocytes fr om Salmo irideus was studied by following their susceptibility to hemo lysis and measuring steady-state fluorescence anisotropy of the fluore scent probe, 1,6-diphenyl-1,3,5-hexatriene (DPH) on isolated membranes , The hemolytic process was strongly affected by different ethanolamin e derivatives, However, only slight changes in fluorescence anisotropy were detected in these models, therefore, it appears that acylethanol amine derivatives do not produce significant variations in the physico -chemical characteristics of the membrane, The localization of these m olecules in particular microdomains is hypothesized, thus locally modi fying physiological membrane activities.