Mf. Vaezi et al., TRANSIENT PROTEIN-S DEFICIENCY ASSOCIATED WITH CEREBRAL VENOUS THROMBOSIS IN ACTIVE ULCERATIVE-COLITIS, The American journal of gastroenterology, 90(2), 1995, pp. 313-315
Cerebral venous thrombosis is an uncommon complication of ulcerative c
olitis. We report the case of a 29-yr-old female with a recent diagnos
is of ulcerative colitis who suffered stroke secondary to thrombosis o
f the veins of Galen and straight sinus. A search for a hypercoagulabl
e state revealed a nonfamilial transient protein S deficiency. Possibl
e involvement of C4b-binding protein in this hypercoagulable state is
discussed.