Rj. Geise et al., DETERMINATION OF DIAZOLIDINYL UREA IN COSMETIC FORMULATIONS BY CAPILLARY ELECTROPHORESIS, Journal of the Society of Cosmetic Chemists, 45(4), 1994, pp. 173-181
Capillary electrophoresis (CE) is demonstrated for the determination o
f the preservative diazolidinyl urea in cosmetic formulations. The ext
remely high resolving power of CE separates the compound from other de
tectable formulation components. This direct method is an improvement
over traditionally used methods, which involve derivatization/degradat
ion reactions. Due to complex matrices, the method of standard additio
ns is used for quantitation. A negative charge is effected by the use
of berate buffer (pH 9.3), and diazolidinyl urea elutes at ca. 4 minut
es with detection at 215 nm.