DETERMINATION OF DIAZOLIDINYL UREA IN COSMETIC FORMULATIONS BY CAPILLARY ELECTROPHORESIS

Capillary electrophoresis (CE) is demonstrated for the determination o f the preservative diazolidinyl urea in cosmetic formulations. The ext remely high resolving power of CE separates the compound from other de tectable formulation components. This direct method is an improvement over traditionally used methods, which involve derivatization/degradat ion reactions. Due to complex matrices, the method of standard additio ns is used for quantitation. A negative charge is effected by the use of berate buffer (pH 9.3), and diazolidinyl urea elutes at ca. 4 minut es with detection at 215 nm.