BACKGROUND: The open abdomen technique for the treatment of diffuse pe
ritonitis has gained acceptance. Our approach has been to use the zipp
er technique with daily irrigations, Once the abdominal problem has re
solved, the mesh and zipper are removed. Surgeons are reluctant to reo
perate on patients with such prior treatment because of the anticipati
on of a hostile abdomen, Our study is a retrospective review of 12 pat
ients who were treated with the open abdomen technique. At a later dat
e, they underwent elective reoperation. STUDY DESIGN: The charts of 12
patients were reviewed. After initial injury, the patients were in th
e surgical intensive care unit. Reoperations were performed nine month
s (mean) after discharge from this facility. The reasons for reoperati
on were closure of enteric fistula (five patients) and closure of an o
stomy (seven patients). The abdominal wall was reconstructed in nine p
atients. In the other three patients, the abdomen was entered through
a lateral incision and the bowel was reanastomosed. RESULTS: All of th
e patients survived. There were five complications. Two patients had i
schemic skin grafts successfully treated by hyperbaric oxygen therapy
(HBO). Two patients had ischemic skin flaps that were covering mesh. T
hey responded to HBO with minimal slough of superficial tissue. One pa
tient had a low output fistula that closed after two weeks of total pa
renteral nutrition. CONCLUSIONS: A history of an open abdomen is not a
contraindication to later operation. Bowel continuity can be restored
and abdominal wall reconstruction can be performed safely. This can b
e done as early as three to four months after recovery from the origin
al injury.