Wpf. Fetter et al., SURFACTANT REPLACEMENT THERAPY IN NEONATES WITH RESPIRATORY-FAILURE DUE TO BACTERIAL SEPSIS, Acta paediatrica, 84(1), 1995, pp. 14-16
We describe four newborns (gestational ages 29-37 weeks; birthweights
1380-3040 grams) who were mechanically ventilated for respiratory insu
fficiency because of bacterial sepsis. A beneficial effect of bovine s
urfactant (Alvofact, dosages 50 or 100 mg/kg) was found, as shown by d
ecreases in mean airway pressures and oxygen demands. No side effects
were seen after instillation.