ANALYTICAL POTENTIAL OF NEAR-INFRARED FOURIER-TRANSFORM RAMAN-SPECTRAIN THE DETECTION OF SOLID TRANSITION-METAL CARBONYL STEROID-HORMONES

Near-infrared (NIR) Fourier transform (FT) Raman spectra of four stero id hormones labeled with organometallic fragments, five steroid hormon es and five model organometallic complexes were measured at room tempe rature. The objective was to determine which particular molecular vibr ations of the steroid hormones might be best suited for any future qua ntitative analyses. On the basis of this FT-Raman study, a classificat ion of the most important vibrations as a function of their relative b and intensities is proposed, i.e. nu(Co-2-alkyne) approximate to nu(Co -Co) < nu(C=C) approximate to nu(C-C)(Cp)(Cp = eta(5)-C5H5) < nu(C=O) < nu(C=N).