N. Rasgon et al., AGENESIS OF CORPUS-CALLOSUM AND DEMENTIA OF THE ALZHEIMERS TYPE - A REVIEW AND CASE-REPORT, Canadian journal of psychiatry, 39(7), 1994, pp. 429-432
This paper describes a previously sufficiently functioning 57 year old
man who presented with a recent onset of frontal behaviour. Partial a
genesis of corpus callosum was an incidental finding on a computerized
tomography scan. The EEG was within normal limits and neuropsychologi
cal testing did not reveal any interhemispheric disconnection. A SPECT
-Scan revealed bilateral hypoperfusion, consistent with Alzheimer's de
mentia. Normal functioning up to 50 years of age and a later manifesta
tion of Alzheimer's disease along with agenesis of carpus callosum is
of clinical interest as such as association has not been published.