PRIMARY YOLK-SAC TUMOR OF THE PROSTATE IN A PATIENT WITH KLINEFELTERS-SYNDROME

Primary yolk sac (endodermal sinus) tumor of the prostate is extremely rare with only 2 cases reported in the literature. We describe a case of primary yolk sac tumor of the prostate in a man with Klinefelter's syndrome. Treatment included 4 courses of combination chemotherapy fo llowed by retroperitoneal lymph node dissection, cystoprostatectomy an d ileal conduit urinary diversion. We review the association of Klinef elter's syndrome with extragonadal germ cell tumor along with the mana gement of this rare disease.