A number of studies have commented on the inadvisability of transfusin
g unused blood given by autologous and directed donors to patients oth
er than those for whom the blood was originally given (crossing over).
It has been stated that these bloods are dangerous and should not be
used for allogeneic transfusion. To test this hypothesis, data were ta
ken from a pool of hospital donors. These show that if the donor group
s of allogeneic, directed, and autologous are further divided into set
s of first time and multiple donors, the incident of infectious diseas
e markers is no higher in one set than the other except for the alloge
neic first time donor. Therefore, the ''dangerous'' donor is actually
more likely a first time donor. Following this reasoning, the use of a
ll blood from first time donors should be suspect.